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Each Has A Molecular Weight Of Approximately 55 Kda.

The nuclear counterstain is dapi (blue). Tubb3 protein expression is restricted to neurons. This gene encodes a class iii member of the beta tubulin protein family.

Our Beta Iii Tubulin Monoclonal, Polyclonal And Recombinant Monoclonal Antibodies Are Developed In Mouse And Rabbit.

The phosphate is added at a serine and perhaps a tyrosine near the c. As compared to somatic organs and tissues, betaiii is abundant in the central and peripheral nervous systems (cns and pns) where it is promine. Tubulins, major components of the cellular cytoskeleton, form microtubules that are critical for cellular structure, migration, cell division, and intracellular trafficking.

While General Tubulins Play A Role In A Wide Range Of Cellular Processes (Mitosis, Motility, Etc) Beta Tubulin Iii Is Specifically Localized To Neurons.

There are at least three types of tubulins: Cells were fixed in paraformaldehyde, permeabilized with 0.25% triton x100/pbs. Find the beta iii tubulin antibody that fits your needs.

Specifically, Of The Seven Beta Isotypes, The Phosphorylated One Is Beta Iii, The Isotype Found Almost Entirely In Neurons.

Mutations in this gene are the. Beta tubulin 3/ tuj1 antibody detects beta tubulin 3/ tuj1 protein by western blot analysis. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules.

Tubb3 Plays A Critical Role In Proper Axon Guidance And Maintenance.

This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. These antibodies have been verified by knockout, relative expression, cell treatment and independent antibody to confirm specificity to beta iii tubulin. Tubulin is the major constituent of microtubules.